Norgesic® is a multimodal agent. It is an opioid-free pain reliever that combines 3 medications into one pill to help relieve mild to moderate acute musculoskeletal pain.
Each Norgesic® tablet contains the following:
Orphenadrine Citrate 25 mg - Orphenadrine is a muscle relaxant, which helps to reduce muscle tension and pain due to strains, overuse, and other injuries.
Aspirin 385 mg - Aspirin is a nonsteroidal anti-inflammatory drug (NSAID). Aspirin is effective in alleviating pain, swelling, and fevers.
Caffeine 30 mg - Caffeine is a stimulant. It is often combined with other pain medications, such as aspirin, to increase pain relief.
Norgesic® is a multimodal agent for treatment of mild to moderate acute musculoskeletal pain.
Aspirin should be used with extreme caution in the presence of peptic ulcers and coagulation abnormalities. Rare GI hemorrhage due to the aspirin content may be associated with the administration of Norgesic®.
According to a Cochrane meta-analysis of more than 7,000 patients, caffeine was found to have a synergistic effect on pain relief when added as an analgesic adjuvant.
Side effects of Norgesic® Tablets are those seen with aspirin and caffeine or those usually associated with mild anti-cholinergic agents. These may include tachycardia, palpitation, urinary hesitancy or retention, dry mouth, blurred vision, dilation of the pupil, increased intraocular tension, weakness, nausea, vomiting, headache, dizziness, constipation, drowsiness, and rarely, urticaria and other dermatosis. Infrequently, an elderly patient may experience some degree of confusion. Mild central excitation and occasional hallucinations may be observed. These mild side effects can usually be eliminated by reduction in dosage. One case of aplastic anemia associated with the use of orphenadrine citrate, aspirin and caffeine has been reported. No causal relationship has been established. Rare G.I. hemorrhage due to aspirin content may be associated with the administration of Norgesic® Tablets. Some patients may experience transient episodes of light-headedness, dizziness or syncope.
Norgesic® is available at many independent and retail pharmacies. If you are unable to find this product locally, Sterling Specialty Pharmacy is able to mail to patients across the US. Should your healthcare
provider choose to prescribe Norgesic®,
click here to download an information sheet
to give to them.
E-scribe #: 2433693
Pharmacy Name: Sterling Specialty Pharmacy, Mendota Heights, MN
Phone Number: 888-618-4126
Fax Number: 866-588-0371
What is the most important information I should know about Norgesic®?
Norgesic® tablets may cause serious side effects, including:
Stop taking Norgesic® and call your healthcare provider or get emergency help right away if you have any of these symptoms: rash, fever, trouble breathing, or swelling of the face, lips, tongue, or throat.
Use caution until you know how Norgesic® affects you. It may impair your ability to drive or use other machinery.
Before taking Norgesic®, tell your healthcare provider about all your medical conditions, including active viral infection (such as chicken pox, flu, or flu-like symptoms), stomach ulcer, bleeding problems, or pregnancy (or plans to become pregnant).
Talk to your healthcare provider if you are considering taking Norgesic® during pregnancy. You should not take Norgesic® after 29 weeks of pregnancy.
Common side effects of Norgesic® include increased heart rate (tachycardia), strong or rapid heartbeat (palpitations), trouble urinating (urinary hesitancy or retention), dry mouth, blurred vision, weakness, nausea, vomiting, headache, dizziness, constipation, or drowsiness.
These are not all the possible side effects of Norgesic®. Please see the Full Prescribing Information for the complete list of side effects or speak with your healthcare provider for medical advice or more information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Norgesic® is a prescription medicine for the relief of mild to moderate pain due to acute disorders of the muscles, bones, joints, ligaments, or tendons. Norgesic® tablets should be used along with rest, physical therapy, and other measures to help relieve discomfort associated with such conditions. Norgesic® is not recommended in children under 12 years of age.
Please see the Full Prescribing Information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
